| HyPer |
Ratiometric sensor for high-specific detection of intracellular hydrogen peroxide |
Rise in H2O2 concentration leads to decrease in sensor excitation peak at 420 nm and proportional increase in excitation peak at 500 nm |
- Ratiometric measurement
- High specificity and sensitivity
- Capability of targeting the sensor to the specific cell compartments
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| Case12 |
High dynamic range sensor for detection of intracellular Ca2+ changes |
Rise in Ca2+ concentration leads to significant increase of the reporter�s brightness |
- High dynamic range
- Relatively high pH stability
- Capability of targeting the sensor to the specific cell compartments
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| Casper3-BG |
Highly sensitive FRET-based sensors for early detection of caspase-3 activity onset |
Activation of caspase-3 leads to elimination of FRET between TagBFP and TagGFP2 fluorescent proteins, resulting in the decrease of green and increase of blue fluorescence |
- High sensitivity
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| Casper3-GR |
Activation of caspase-3 leads to elimination of FRET between TagGFP and TagRFP fluorescent proteins, resulting in the decrease of red and increase of green fluorescence |
- High sensitivity
- Proven suitability for FLIM-based screenings
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