Genetically-encoded photosensitizer KillerOrange

- Blue and green light-induced production of reactive oxygen species
- Direct expression in cells, easy targeting to various subcellular compartments
- No exogenous chemical compounds required for chromophore maturation
- Not toxic before activation by blue or green light irradiation
- Recommended for selective light-induced protein inactivation and cell killing

Main properties

Blue line – excitation (em@600 nm), Orange line – emission (ex@510 nm) Download KillerOrange spectra (xls)

CHARACTERISTIC * Brightness is a product of extinction coefficient and quantum yield, divided by 1000. Molecular weight, kDa 27 Polypeptide length, aa 239 Structure dimer Aggregation no Maturation rate at 37°C fast Activating light blue or green (e.g. 450-540 nm) Fluorescence color orange Excitation maximum, nm 512 Emission maximum, nm 555 Quantum yield 0.42 Extinction coefficient, M-1cm-1 41200 Brightness* 17.3