Genetically-encoded photosensitizer KillerRed

- Light-induced production of reactive oxygen species
- Direct expression in cells, easy targeting to various subcellular compartments
- No exogenous chemical compounds required for chromophore maturation
- Not toxic before activation by green or orange light irradiation
- Recommended for selective light-induced protein inactivation and cell killing

Main properties

Normalized excitation (green line) and emission (red line) spectra. Download KillerRed spectra (xls)

CHARACTERISTIC * Brightness is a product of extinction coefficient and quantum yield, divided by 1000. Molecular weight, kDa 27 Polypeptide length, aa 239 Structure dimer Aggregation no Maturation rate at 37°C fast Activating light green or orange (e.g. 540-590 nm) Fluorescence color red Excitation maximum, nm 585 Emission maximum, nm 610 Quantum yield 0.25 Extinction coefficient, M-1cm-1 45 000 Brightness* 11.3