Available variants and fusions
VariantDescriptionRelated vectorCat.#Click for image
Case12-cyto Case12 codon usage is optimized for high expression in mammalian cells [Haas et al., 1996], but it can be successfully expressed in other heterological systems.
When expressed in mammalian cells, this variant is evenly distributed throughout the cytosol and the nucleus.
pCase12-cyto* FP991
Case12-mito Mitochondrial targeting sequence derived from subunit VIII precursor of human cytochrome C oxidase [Rizzuto et al., 1989; Rizzuto et al., 1995] is fused to Case12 N-terminus. When expressed in mammalian cells, this variant is localized in mitochondria. pCase12-mito* FP992